Related Experiment Video
Updated: Mar 22, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Renal Mass Biopsy: Always, Sometimes, or Never?
Alexander Kutikov1, Marc C Smaldone1, Robert G Uzzo1
1Division of Urologic Oncology, Department of Surgical Oncology, Fox Chase Cancer Center, Temple University Health System, Philadelphia, PA, USA.
Renal mass biopsy is a valuable diagnostic tool, but it often fails to change patient management. Routine use is not recommended for all patients outside of specific research studies.
Area of Science:
- Urology
- Nephrology
- Diagnostic Imaging
Background:
- Renal mass biopsy (RMB) is an established diagnostic procedure for evaluating kidney lesions.
- The clinical utility of RMB is debated due to its impact on patient management.
Discussion:
- Current RMB practices frequently do not lead to changes in clinical decision-making for the majority of patients.
- This suggests a potential overutilization or need for refinement in RMB indications.
Key Insights:
- Despite being a useful tool, RMB's current application does not alter management in most cases.
- The effectiveness of RMB is limited when applied broadly without specific clinical protocols.
Outlook:
- Further research is needed to identify specific patient subgroups who benefit most from RMB.
- Development of improved RMB techniques or interpretation guidelines may enhance its clinical impact.
- Clinical protocols should guide the selective use of RMB in specific scenarios.
Related Concept Videos
Imaging Studies IV: Magnetic Resonance Imaging
Nursing Assessment of the Genitourinary System II: Inspection and Palpation
Imaging Studies VII: Vascular Imaging
Imaging Studies II: Ultrasonography
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Myocarditis II: Clinical Features and Diagnostic Tests

