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Related Concept Videos

Electrodeposition01:08

Electrodeposition

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Electrodeposition is a technique used to separate an analyte from interferents by electrochemical processes. Here, the analyte is a metal ion that can be deposited on an electrode immersed in the sample solution. The electrochemical setup consists of an anode and a cathode. When an electric current is applied to the setup, oxidation occurs at the anode. At the cathode, which consists of a large metal surface, metal ions undergo reduction and deposit onto the surface.
Electrodeposition can...
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Colloidal precipitates

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The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
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The Electrical Double Layer01:30

The Electrical Double Layer

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In the region where two bulk phases meet, an intricate electric charge distribution arises due to charge transfer, ion adsorption, molecular orientation, and charge distortion. This complex distribution is commonly referred to as the electrical double layer.When a solid electrode interfaces with ions in an electrolyte solution, the speed of electron transfer dictates the rates of oxidation and reduction. The electrode acquires a charge through the escape of atoms into the solution as cations or...
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Factors Influencing Drug Absorption: Pharmaceutical Parameters01:28

Factors Influencing Drug Absorption: Pharmaceutical Parameters

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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
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Electrogravimetric Analysis: Overview01:30

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Electrogravimetric analysis measures the weight of an analyte deposited electrolytically onto a suitable working electrode. This method involves applying a potential to a pre-weighed electrode submerged in a solution, which results in the desired substance being deposited through reduction at the cathode or oxidation at the anode. The electrode's weight is recorded after deposition, and the difference in weight gives the analyte's weight in the solution.
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Capillary Electrophoresis: Applications01:30

Capillary Electrophoresis: Applications

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Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
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Vapor Phase Deposition of Electroactive Poly(3,4-ethylenedioxythiophene) onto Electrospun Commodity Polymer Nanofibers
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Electrostatic powder coating: Principles and pharmaceutical applications.

Leena Kumari Prasad1, James W McGinity1, Robert O Williams1

  • 1College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Campus Mail Code A1920, Austin, TX 78712, USA.

International Journal of Pharmaceutics
|April 18, 2016
PubMed
Summary
This summary is machine-generated.

Pharmaceutical powders can build static charge, causing processing issues. Understanding and controlling this electrostatic charging enables advanced techniques like electrostatic powder coating for pharmaceutical dosage forms.

Keywords:
Dry powder coatingElectrostatic powder coatingElectrostatic powder depositionOral filmPowder charging

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Area of Science:

  • Pharmaceutical science
  • Materials science
  • Chemical engineering

Background:

  • Many pharmaceutical powders are insulating and prone to electrostatic charging.
  • This charging phenomenon presents safety hazards and processing challenges.
  • Recent advancements allow for the controlled use of powder charging in pharmaceutical manufacturing.

Purpose of the Study:

  • To review the principles of electrostatic powder coating.
  • To highlight research on applying this technology to pharmaceutical dosage forms.
  • To bridge knowledge from the finishing industry to pharmaceutical applications.

Main Methods:

  • Literature review of electrostatic powder coating principles.
  • Summary of research on pharmaceutical powder charging.
  • Analysis of electrostatic powder coating applications in drug delivery systems.

Main Results:

  • Electrostatic powder coating is a viable technique for pharmaceutical applications.
  • Understanding powder charging improves processing control and product performance.
  • Existing knowledge from the finishing industry is transferable to pharmaceutical contexts.

Conclusions:

  • Electrostatic powder coating offers a promising approach for pharmaceutical dosage form preparation.
  • Further research can optimize this technique for enhanced drug delivery.
  • Control over electrostatic charging is key to leveraging this technology effectively.