Cardiac Manifestation of Acute Lymphoblastic Leukemia
Rudolf A Werner1, Martina Rudelius, Annette Thurner
1From the *Department of Nuclear Medicine, †Comprehensive Heart Failure Center, University Hospital Würzburg; ‡Institute for Pathology, University of Würzburg; and §Institute for Radiology, University Hospital Würzburg, Würzburg, Germany.
Abstract:
Here, we report on a 38-year-old man with unclear right heart failure. Imaging with cardiac MRI and combined PET/CT with F-FDG revealed a hypermetabolic mass extending from the right ventricle to the atrium. In addition, intense glucose utilization throughout the bone marrow was noted. Biopsies of both bone marrow and cardiac mass were performed and revealed precursor B-cell acute lymphoblastic leukemia with gross leukemic infiltration of the myopericardium, a rare manifestation of acute lymphoblastic leukemia at initial diagnosis.
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