PERSISTENT PLACOID MACULOPATHY IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
Related Experiment Video
Updated: Mar 22, 2026
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Nathalie Puche1, Ruxandra Hera, Celine Terrada
1*Centre Alpes Rétine, Montbonnot-Grenoble, France; †Centre Ophtalmologique Roule-Peretti, Neuilly sur Seine; ‡Department of Ophtalmology, Hôpital Lariboisière, Paris, France; and §Department of Ophtalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est.
Purpose:
To describe the case of a patient presenting with persistent placoid maculopathy imaged with optical coherence tomography angiography.
Methods:
Case report of a 72-year-old man who presented with blurred vision in his right eye. fundus photography, fluorescein angiography, infracyanine green angiography, fundus autofluorescence imaging, spectral domain optical coherence tomography, optical coherence tomography angiography, and split spectrum amplitude decorrelation angiography were performed. The diagnosis was made based on ophthalmological manifestations and multimodal imaging.
Results:
The spectral domain optical coherence tomography image of the right eye revealed disruption of the ellipsoid layers, and an underlying sliver of hyporeflectance. In the left eye, there were no obvious changes on spectral domain optical coherence tomography. In both eyes, infracyanine green angiography showed hypocyanescence of the lesions, persisting throughout late phases. In optical coherence tomography angiography, imaging of the choroidal capillary layers revealed hyposignal lesions, topographically corresponding exactly to hypocyanescent lesions on infracyanine green angiography.
Conclusion:
In this patient, a distinct hyposignal on optical coherence tomography angiography, combined with hypocyanescence on infracyanine green angiography, was interpreted as indicating focal hypoperfusion of the choriocapillaris.
