Relation between curability and tumor volume in a murine carcinoma and sarcoma

Tumor control doses (TCD50) using single 60CO doses were determined on C3HBA adenocarcinoma and Dunn osteosaroma ranging in size from microscopic pulmonary colonies (3 X 13(-5) mm3) to palpable subcutaneous tumors (300 mm3) in the hind limb. The power function TCD50 =23.57 TV0.15, with TCD50 in GY and TV (tumor volume) in mm3, fits the data for both tumors over the entire range of tumor volumes used.