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Updated: Mar 22, 2026
11:35
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
58.9K
Managing Disability in Progressive Multiple Sclerosis
Divyanshu Dubey1, Peter Sguigna1, Olaf Stüve2,3
1Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Current Treatment Options in Neurology
|April 20, 2016
Summary
Managing symptoms like depression and cognitive decline is crucial for progressive multiple sclerosis (MS) patients. This review outlines key strategies for addressing common comorbidities to improve quality of life in progressive MS.
Area of Science:
- Neurology
- Clinical Medicine
Background:
- Progressive forms of multiple sclerosis (MS) present diverse symptoms impacting patient quality of life.
- Current immunomodulatory therapies lack approval for progressive MS, with focus shifting to symptomatic management.
- Limited research exists on symptomatic management strategies specifically for progressive MS.
Purpose of the Study:
- To review common comorbidities associated with progressive MS.
- To outline important strategies for the symptomatic management of these comorbidities.
Main Methods:
- Literature review of studies on symptomatic management in progressive MS.
- Analysis of data, including that from relapsing MS studies, to inform management strategies.
Main Results:
- Identified common comorbidities: depression, cognitive decline, sleep, bladder, and sexual dysfunction, and spasticity.
- Highlighted the importance of understanding therapy risks, benefits, and limitations for patient care.
Conclusions:
- Symptomatic management of comorbidities is a primary focus for improving quality of life in progressive MS.
- Further research is needed to establish evidence-based symptomatic management protocols for progressive MS.
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