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Simultaneous multislice accelerated interleaved EPI DWI using generalized blipped-CAIPI acquisition and 3D K-space

Erpeng Dai1, Xiaodong Ma1, Zhe Zhang1

  • 1Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China.

Magnetic Resonance in Medicine
|April 20, 2016
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Summary

This study introduces a new method to accelerate interleaved echo-planar imaging diffusion-weighted imaging (iEPI DWI) using simultaneous multislice (SMS) technology. The technique effectively combines slice unfolding and phase correction, improving imaging efficiency without sacrificing image quality.

Keywords:
SMS 3D k-spaceblipped-CAIPIdiffusion-weighted imaginghigh-resolution DWIinterleaved EPIsimultaneous multislice

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Area of Science:

  • Magnetic Resonance Imaging
  • Diffusion-Weighted Imaging

Background:

  • Simultaneous multislice (SMS) accelerates single-shot echo-planar imaging (ssh-EPI) DWI.
  • Applying SMS to interleaved echo-planar imaging (iEPI) DWI faces challenges in combining slice unfolding and intershot phase correction.

Purpose of the Study:

  • To propose a novel acquisition and reconstruction method for SMS-accelerated high-resolution iEPI DWI.
  • To address the obstacles in applying SMS to multishot DWI.

Main Methods:

  • Generalized the blipped-controlled aliasing in parallel imaging (blipped-CAIPI) for iEPI.
  • Designed an SMS 3D navigator acquisition for intershot phase variations.
  • Performed simultaneous slice unfolding and intershot phase correction in a 3D k-space.

Main Results:

  • Successfully unfolded simultaneously excited slices.
  • Effectively suppressed artifacts from intershot phase variations.
  • Achieved improved imaging efficiency with comparable image quality to unaccelerated iEPI DWI.

Conclusions:

  • The proposed method effectively accelerates multishot high-resolution DWI.
  • This technique may benefit neuroscience research and clinical diagnosis.