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Hydrogen Bonds

Hydrogen Bonds

A hydrogen bond is formed when a weakly positive hydrogen atom already bonded to one electronegative atom (for example, the oxygen in the water molecule) is attracted to another electronegative atom from another polar molecule, such as water (H2O), hydrogen fluoride (HF), or ammonia (NH3). The huge electronegativity difference between the H atom (2.1) and the atom to which it is bonded (4.0 for an F atom, 3.5 for an O atom, or 3.0 for an N atom), combined with the very small size of an H atom...

Hydrogen Bonds

Hydrogen Bonds

Hydrogen bonds are weak attractions between atoms that have formed other chemical bonds. One of these atoms is electronegative, like oxygen, and has a partial negative charge. The other is a hydrogen atom that has bonded with another electronegative atom and has a partial positive charge.
Hydrogen Bonds Control the World!
Because hydrogen has very weak electronegativity when it binds with a strongly electronegative atom, such as oxygen or nitrogen, electrons in the bond are unequally shared....

Noncovalent Attractions in Biomolecules

Noncovalent Attractions in Biomolecules

Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
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Noncovalent Attractions in Biomolecules

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¹H NMR: Long-Range Coupling

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The coupling interactions of nuclei across four or more bonds are usually weak, with J values less than 1 Hz. While these are usually not observed in spectra, the presence of multiple bonds along the coupling pathway can result in observable long-range coupling.
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Related Experiment Video

Updated: Mar 22, 2026

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Published on: February 15, 2016

Mapping Buried Hydrogen-Bonding Networks.

John C Thomas^1,2, Dominic P Goronzy^1,2, Konstantin Dragomiretskiy^2,3

¹Department of Chemistry and Biochemistry, University of California, Los Angeles , Los Angeles, California 90095, United States.

|April 21, 2016

Summary

This summary is machine-generated.

We mapped buried hydrogen bonds and S-Au bonds in self-assembled monolayers. Amide hydrogen bonds were found to extend across molecular domains, revealing directional bonding at the nanoscale.

Keywords:

disorder hydrogen bonding image analysis scanning tunneling microscopy segmentation self-assembled monolayers self-assembly spectroscopic imaging two-dimensional variational mode decomposition

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Last Updated: Mar 22, 2026

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

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Quantification of Hydrogen Concentrations in Surface and Interface Layers and Bulk Materials through Depth Profiling with Nuclear Reaction Analysis

Quantification of Hydrogen Concentrations in Surface and Interface Layers and Bulk Materials through Depth Profiling with Nuclear Reaction Analysis

Published on: March 29, 2016

Area of Science:

Surface science
Supramolecular chemistry
Nanotechnology

Background:

Self-assembled monolayers (SAMs) are crucial for surface functionalization.
Understanding buried interfaces is key to controlling SAM properties.
Hydrogen bonding plays a significant role in molecular assembly.

Purpose of the Study:

To map buried hydrogen-bonding networks in 3-mercapto-N-nonylpropionamide SAMs on Au{111}.
To determine the orientation and directional bonding of molecular segments.
To investigate the role of hydrogen bonds in molecular organization.

Main Methods:

Simultaneous mapping of buried S-Au bonds and hydrogen-bonding networks with submolecular resolution.
Analysis of the exposed interface.
Application of two-dimensional mode-decomposition techniques.

Main Results:

Successfully mapped buried S-Au bonds and linear hydrogen-bonding networks.
Determined molecular segment orientations and directional bonding.
Observed amide-based hydrogen bonds extending across molecular domain boundaries and disordered regions.

Conclusions:

Provides a comprehensive understanding of buried interfaces in SAMs.
Highlights the importance of hydrogen bonding in directing molecular assembly and overcoming local disorder.
Offers insights into designing functional surfaces with controlled molecular orientations.