Jove
Visualize
Contact Us

Related Experiment Videos

Primary hyperparathyroidism presenting as a proximal myopathy.

R D Rollinson, B S Gilligan

    Australian and New Zealand Journal of Medicine
    |August 1, 1977
    PubMed
    Summary

    Primary hyperparathyroidism caused progressive muscle weakness and severe bone disease in a patient. Surgical removal of a parathyroid adenoma resolved these symptoms, restoring muscle strength and bone health.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The Lhermitte phenomenon: variant forms and their significance.

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2008
    Same author

    HTLV-I associated myelopathy in a Seychellois immigrant.

    The Medical journal of Australia·1993
    Same author

    Thrombolytic therapy in vertebrobasilar occlusion.

    Clinical and experimental neurology·1992
    Same author

    Intraventricular infusion of Dopamine in Parkinson's disease.

    Annals of neurology·1989
    Same author

    Obstructive hydrocephalus caused by multiple sclerosis.

    Clinical and experimental neurology·1989
    Same author

    Impact of a pharmacokinetics consultation service on clinical outcomes in an ambulatory-care epilepsy clinic.

    American journal of hospital pharmacy·1988
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Endocrinology
    • Neuromuscular Medicine
    • Metabolic Bone Disease

    Background:

    • Primary hyperparathyroidism is a common endocrine disorder often associated with metabolic bone disease.
    • Proximal myopathy can be an underrecognized manifestation of hyperparathyroidism.

    Observation:

    • A 46-year-old female experienced three years of progressive proximal muscle weakness.
    • Clinical presentation included asymptomatic myopathy, biochemical abnormalities, and radiological evidence suggestive of severe metabolic bone disease.

    Findings:

    • Multichannel screening and imaging confirmed primary hyperparathyroidism.
    • Surgical excision of a parathyroid adenoma was performed.

    Implications:

    • Parathyroid adenoma removal led to significant improvement in muscle strength.
    • Metabolic bone disease and associated bony changes demonstrated regression post-surgery.
    • Highlights the importance of considering and managing hyperparathyroidism in cases of unexplained myopathy and bone disease.

    Related Experiment Videos