Related Experiment Videos
The unequivocal determination of lactic acid using a one-dimensional zero-quantum coherence-transfer technique
D M Doddrell1, I M Brereton, L N Moxon
1Department of Chemistry, University of Queensland, St. Lucia, Australia.
Magnetic Resonance in Medicine
|January 1, 1989
Abstract:
A method based on zero-quantum coherence transfer for spectral editing of metabolites in aqueous solution in a one-dimensional experiment is described. Water suppression factors of approximately 8000 were achieved by the use of pulsed B0 field gradients and excellent editing was obtained in a single acquisition. The methyl resonances of both lactate and acetaldehyde were readily observed in a mouse brain homogenate by generating zero-quantum coherence using Gaussian pulses for selective excitation of the respective CH resonances.