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Alarmins and Antitumor Immunity.

Yingjie Nie1, De Yang2, Joost J Oppenheim3

  • 1Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick National Laboratory for Cancer Research, Frederick, Maryland; Guizhou Provincial Peoples' Hospital, Guiyang, Guizhou Province, China.

Clinical Therapeutics
|April 23, 2016
PubMed
Summary

Alarmins are immune system alarm signals that help fight tumors. These molecules, like High-mobility group nucleosome-binding protein 1 (HMGN1), can be used as cancer biomarkers and in cancer treatment.

Keywords:
alarminbiomarkerdamage-associated molecular patternsimmune responsepattern recognition receptortumor immunity

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