Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 22, 2026

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications
10:56

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications

Published on: February 6, 2016

14.6K

Laser-synthesized oxide-passivated bright Si quantum dots for bioimaging.

M B Gongalsky1, L A Osminkina1,2, A Pereira3

  • 1Lomonosov Moscow State University, Department of Physics, 119991 Moscow, Russia.

Scientific Reports
|April 23, 2016
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Formation of inverse electron distribution function in glow discharges with hollow cathode.

Physical review. E·2026
Same author

Crystal structure and physical properties of shchurovskyite-related K<sub>2</sub>CaCu<sub>6</sub>O<sub>2</sub>(PO<sub>4</sub>)<sub>4</sub>.

Dalton transactions (Cambridge, England : 2003)·2026
Same author

Measurement of Two-Point Energy Correlators within Jets in p+p Collisions at sqrt[s]=200  GeV.

Physical review letters·2025
Same author

Single-cell transcriptomic profiling of immune landscape in triple-negative breast cancer during neoadjuvant chemotherapy.

NPJ systems biology and applications·2025
Same author

Erratum: Measurement of the Sixth-Order Cumulant of Net-Proton Multiplicity Distributions in Au+Au Collisions at sqrt[s_{NN}]=27, 54.4, and 200 GeV at RHIC [Phys. Rev. Lett. 127, 262301 (2021)].

Physical review letters·2025
Same author

Erratum: Nonmonotonic Energy Dependence of Net-Proton Number Fluctuations [Phys. Rev. Lett. 126, 092301 (2021)].

Physical review letters·2025

Ultrapure silicon quantum dots offer bright, non-toxic bioimaging near 800nm. These water-dispersible nanoparticles are ideal for cell imaging and potential cancer theranostics without harmful synthesis by-products.

Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Materials Science

Background:

  • Crystalline silicon (Si) nanoparticles show promise for bioimaging via photoluminescence (PL).
  • Traditional synthesis methods often result in toxic residues, limiting their biomedical applications.
  • Efficient PL emission in aqueous suspension is a key challenge for Si nanoparticles.

Purpose of the Study:

  • To develop ultrapure, water-dispersible silicon quantum dots (QDs) for bioimaging.
  • To investigate the photoluminescent properties of these QDs in the near-infrared (NIR) region.
  • To evaluate the biocompatibility and cellular uptake of the synthesized Si QDs for theranostic applications.

Main Methods:

  • Laser ablation of crystalline Si targets in helium to synthesize Si QDs.

More Related Videos

Compact Quantum Dots for Single-molecule Imaging
17:14

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

18.8K
Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping
14:58

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping

Published on: June 3, 2015

15.5K

Related Experiment Videos

Last Updated: Mar 22, 2026

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications
10:56

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications

Published on: February 6, 2016

14.6K
Compact Quantum Dots for Single-molecule Imaging
17:14

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

18.8K
Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping
14:58

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping

Published on: June 3, 2015

15.5K
  • Ultrasound-assisted dispersion of Si QDs in physiological saline.
  • Exciton photoluminescence (PL) imaging in living cells.

    • Main Results:

    • Synthesized Si QDs are water-dispersible and exhibit bright exciton PL near 800 nm, within the window of relative tissue transparency.
    • The laser ablation method avoids toxic by-products, ensuring ultrapurity.
    • Demonstrated efficient contrast in living cells, with QDs accumulating near the cell membrane and cytoplasm without inducing cytotoxicity.

    Conclusions:

    • Ultrapure laser-synthesized Si QDs are a non-toxic, highly effective tool for bioimaging.
    • These Si QDs show potential for cancer theranostic applications due to their imaging capabilities and potential for therapeutic delivery.
    • The developed synthesis method offers a safe and efficient route to producing advanced nanomaterials for biomedical use.