Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

489
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
489
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

609
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
609
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

507
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
507
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

310
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
310
Pericarditis IV: Nursing Management01:25

Pericarditis IV: Nursing Management

535
Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
535
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

325
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
325

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidental cardiac mass: when the past influences the future.

European heart journal. Imaging methods and practice·2026
Same author

One echocardiographic or hemodynamic parameter improves mortality prediction by the ESC/ERS four-strata model: a flexible approach to follow-up risk stratification in pulmonary arterial hypertension.

European heart journal. Quality of care & clinical outcomes·2026
Same author

Arrhythmic Myocarditis and Prevention of Sudden Cardiac Death: Current Evidence, Risk Stratification, and Management.

Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese·2026
Same author

Management of pericarditis: recent advances.

Polish archives of internal medicine·2026
Same author

[Ten clinical questions about recurrent or incessant pericarditis].

Giornale italiano di cardiologia (2006)·2026
Same author

Left atrial strain and fibrosis in primary mitral regurgitation: asynchronous markers of atrial remodelling?

International journal of cardiology·2026

Related Experiment Video

Updated: Mar 22, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

4.5K

Recurrent Pericarditis: Modern Approach in 2016.

Massimo Imazio1,2, Yehuda Adler3,4, Philippe Charron5

  • 1Cardiology Department, Maria Vittoria Hospital, Torino, Italy. massimo_imazio@yahoo.it.

Current Cardiology Reports
|April 25, 2016
PubMed
Summary

Recurrent pericarditis affects one-third of patients and is often autoimmune. Treatment progresses from anti-inflammatories and colchicine to advanced therapies like azathioprine, IVIG, anakinra, or pericardiectomy if medical options fail.

Keywords:
ColchicinePericarditisPrognosisRecurrenceTherapy

More Related Videos

Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
10:05

Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine

Published on: July 7, 2016

9.0K
An Intact Pericardium Ischemic Rodent Model
07:15

An Intact Pericardium Ischemic Rodent Model

Published on: September 2, 2021

3.1K

Related Experiment Videos

Last Updated: Mar 22, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

4.5K
Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
10:05

Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine

Published on: July 7, 2016

9.0K
An Intact Pericardium Ischemic Rodent Model
07:15

An Intact Pericardium Ischemic Rodent Model

Published on: September 2, 2021

3.1K

Area of Science:

  • Cardiology
  • Immunology
  • Internal Medicine

Background:

  • Recurrent pericarditis is a frequent complication, affecting approximately one-third of patients post-initial episode.
  • The presumed pathogenesis involves autoimmune and/or autoinflammatory mechanisms.
  • Managing refractory cases presents a significant clinical challenge.

Purpose of the Study:

  • To outline a stepwise therapeutic approach for recurrent pericarditis.
  • To discuss established and emerging treatment options.
  • To provide guidance on managing corticosteroid-dependent and colchicine-resistant cases.

Main Methods:

  • Review of current therapeutic strategies for recurrent pericarditis.
  • Discussion of pharmacological interventions including NSAIDs, colchicine, corticosteroids, azathioprine, IVIG, and anakinra.
  • Consideration of surgical intervention (pericardiectomy) for refractory cases.

Main Results:

  • Initial management involves physical restriction and anti-inflammatory drugs (aspirin/NSAID) plus colchicine.
  • Corticosteroids are reserved for specific indications or treatment failures.
  • Advanced medical options include azathioprine, IVIG, and anakinra for refractory cases.
  • Pericardiectomy is the final option for patients unresponsive to or intolerant of medical therapies.

Conclusions:

  • A stepwise approach is crucial, starting with NSAIDs and colchicine, escalating to corticosteroids, then advanced medical therapies.
  • Azathioprine, IVIG, and anakinra represent evidence-based options for refractory recurrent pericarditis.
  • Pericardiectomy should be considered in specialized centers for patients with treatment failure or intolerance.