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Related Concept Videos

Three-Dimensional Microscopy in Microbiology01:28

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Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...
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Biophotonic Tools in Cell and Tissue Diagnostics.

Michael Brownstein1, Robert A Hoffman2, Richard Levenson3

  • 1The J. Craig Venter Institute.

Journal of Research of the National Institute of Standards and Technology
|April 26, 2016
PubMed
Summary
This summary is machine-generated.

Advancing biophotonics requires robust measurement tools for cell and tissue diagnostics. A National Institute of Standards and Technology workshop identified critical needs to enhance U.S. competitiveness in this field.

Keywords:
biophotonicsflow cytome-tryimagingmicroarrayoptical coherence tomography

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Area of Science:

  • Biophotonics
  • Medical Diagnostics
  • Optical Measurement

Background:

  • Biophotonics is rapidly advancing, necessitating improved measurement tools for U.S. competitiveness.
  • The National Institute of Standards and Technology (NIST) sponsored a workshop to address these needs.
  • The workshop focused on diagnostic techniques utilizing photon-biological system interactions.

Purpose of the Study:

  • To identify and evaluate near- and far-term measurement needs in biophotonic cell and tissue diagnostics.
  • To contribute to a larger national measurement road-mapping effort.
  • To highlight critical measurement requirements to the scientific community and facilitate solutions.

Main Methods:

  • Convened a workshop with industry representatives and experts.
  • Gathered input through invited presentations and panel discussions.
  • Evaluated current and future measurement requirements for biophotonic diagnostics.

Main Results:

  • Identified key measurement tools essential for the advancement of biophotonics.
  • Documented specific measurement needs for cell and tissue diagnostics.
  • Provided a foundation for a national assessment of the U.S. Measurement System.

Conclusions:

  • Establishing essential measurement tools is crucial for maintaining U.S. leadership in biophotonics.
  • The identified needs will guide future development and investment in biophotonic measurement technologies.
  • Addressing these measurement gaps will enhance the U.S. technology base and global competitiveness.