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Portable Ultraviolet-C Chambers for Inactivation of SARS-CoV-2.

Shelby Claytor¹, Roger Campbell¹, Ashton Hattori¹

¹Georgia Tech Research Institute, Atlanta, GA 30318, USA.

Journal of Research of the National Institute of Standards and Technology

|October 3, 2024

Summary

This summary is machine-generated.

Portable ultraviolet-C (UV-C) chambers were designed for effective disinfection and reuse of personal protective equipment (PPE). This research optimizes UV-C disinfection for critical supplies during pandemics like COVID-19.

Keywords:

LEDs PTFE UV-C disinfection light-emitting diodes mercury vapor lamps prototype ultraviolet ultraviolet-C

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Area of Science:

Engineering
Public Health
Microbiology

Background:

Single-use personal protective equipment (PPE) supply is vulnerable during pandemics, as seen with COVID-19.
Ultraviolet (UV) radiation, particularly UV-C, offers a viable disinfection method for materials.
Safe reuse of PPE is crucial to manage supply chain disruptions.

Purpose of the Study:

To design and optimize portable UV-C disinfection chambers for reliable PPE reuse.
To evaluate UV-C disinfection efficacy against SARS-CoV-2.
To enhance UV-C radiation delivery and develop a disinfection calculator.

Main Methods:

Construction of two portable 280 nm UV-C disinfection chambers (LED and mercury vapor lamp based).
Review of SARS-CoV-2 UV deactivation research (2020-2021).
Installation of UV-reflective polytetrafluoroethylene (PTFE) material to improve radiation uniformity and intensity.
Development of a prototype calculator for UV-C disinfection efficacy.

Main Results:

Two functional portable UV-C chambers with 46 cm x 46 cm x 46 cm internal dimensions were built.
PTFE material installation enhanced UV-C radiation uniformity and intensity.
A calculator prototype was developed to estimate SARS-CoV-2 reduction via UV-C.

Conclusions:

The developed portable UV-C chambers provide a reliable method for PPE disinfection and reuse.
Optimized UV-C delivery systems and calculator tools can support pandemic preparedness.
This approach addresses critical PPE shortages during public health emergencies.