Related Experiment Video
Updated: Mar 22, 2026
Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
Published on: May 10, 2021
Direct Cost-Analysis of Mohs Micrographic Surgery and Traditional Excision for Basal Cell Carcinoma at Initial Margin
Deshan F Sebaratnam1, Bonita Choy, Michael Lee
1*Department of Dermatology, Westmead Hospital, Westmead, Australia; †Skin and Cancer Foundation Australia, Westmead, Australia; ‡Western Clinical School, University of Sydney, Westmead, Australia.
Background:
The literature provides mixed results regarding cost comparisons of Mohs micrographic surgery (MMS) and traditional excision (TE).
Objective:
To complete a prospective cohort study comparing true costs of MMS with projected costs of TE for head and neck basal cell carcinoma (BCC).
Methods:
Patients referred for MMS of biopsy-proven BCC were eligible for inclusion. For each case, surgery with TE was planned before the patient proceeded to MMS. The true costs of MMS were compared with projected costs of TE. All TE patients with inadequate excision were assumed to have subsequent TE, and the cost of the subsequent procedure was assumed to be equal to the first.
Results:
The mean cost of MMS was $628.47 (95% CI: $617.73-$639.21) compared with $587.51 (95% CI: $558.42-$616.59) for TE. This difference of $40.96 to initial margin clearance was significant (z = 4.48, p < .001).
Conclusion:
On average, MMS was found to be $40.96 more expensive than TE in treating BCC-a small but appreciable difference. This being the case, any fiscal comparison must also be tempered with a consideration of effectiveness. Accordingly, further work in the form of a cost-utility study is required to truly define the cost-effectiveness of MMS compared with TE in this setting.
