Stroke and migraine is there a possible comorbidity?

Area of Science:

• Neurology
• Cardiology
• Neuroscience

Background:

• The relationship between migraine and stroke presents a significant challenge for neurologists.
• Migraine is recognized as an independent risk factor for ischemic stroke in specific patient groups.
• Common biochemical mechanisms between migraine and stroke are suggested but not fully understood.

Purpose of the Study:

• To explore the complex association between migraine and stroke.
• To review the classification of migraine-related stroke, including migrainous infarction.
• To investigate potential common pathogenetic factors like patent foramen ovale (PFO).

Main Methods:

• Review of existing literature on migraine and stroke.
• Analysis of classifications for migraine-related stroke.
• Discussion of neuroradiological findings in migraine patients.

Main Results:

• A classification system for migraine-related stroke includes coexisting stroke/migraine, stroke with migraine features, and migraine-induced stroke (e.g., migrainous infarction).
• Patent foramen ovale (PFO) is a notable condition common to both stroke and migraine, potentially contributing to pathogenesis.
• Neuroradiological evidence suggests subclinical lesions in white matter and posterior circulation territories in migraine patients.

Conclusions:

• The association between migraine and stroke remains an open area of research.
• Further investigation is crucial for understanding the epidemiological, pathogenetic, and clinical aspects of migraine-related stroke.
• Clarifying these aspects is fundamental for improved patient management and treatment strategies.