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[Correlation between a blood pressure variability-based scoring system and target organ damage in patients with

Wei Zhu1, Lin Xu, Jian Qiu

  • 11Southern Medical University, Guangzhou 510515, China; 2Department of Cardiology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, China.

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University
|April 27, 2016
PubMed

Insights

A new blood pressure variability scoring system (BPVSS) effectively indicates target organ damage in hypertension patients. Lower scores correlate with more severe heart and blood vessel damage, highlighting BPVSS as a valuable clinical tool.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Vascular Biology

Background:

  • Hypertension is a major risk factor for cardiovascular diseases.
  • Target organ damage is a key indicator of hypertension severity and prognosis.
  • Assessing blood pressure variability (BPV) offers insights into cardiovascular risk.

Purpose of the Study:

  • To evaluate the relationship between a novel blood pressure variability scoring system (BPVSS) and target organ damage in hypertensive patients.
  • To determine if BPVSS can serve as a reliable indicator of subclinical organ damage.

Main Methods:

  • A cohort of 95 essential hypertension inpatients was analyzed.
  • Blood pressure variability indices were correlated with parameters of target organ damage, including interventricular septum thickness (IVSd), left ventricular posterior wall thickness (LVPWd), brachial-ankle pulse wave velocity (baPWV_L/R), and intima-media thickness (IMT_L/R).
  • Patients were stratified into high (BPVSS ≥ 3.9) and low (BPVSS < 3.9) BPVSS groups for comparative analysis.

Main Results:

  • BPVSS showed significant negative correlations with IMT_L/R, IVSd, LVPWd, and baPWV_L/R, indicating that higher BPV (lower BPVSS) is associated with increased organ damage.
  • The low BPVSS group exhibited significantly higher IVSd, LVPWd, baPWV_L/R, and IMT_L/R compared to the high BPVSS group.
  • A significantly higher proportion of carotid plaques was observed in the low BPVSS group.

Conclusions:

  • The blood pressure variability scoring system (BPVSS) is a valuable tool for assessing the severity of target organ damage in hypertension.
  • Elevated blood pressure variability, reflected by lower BPVSS scores, is associated with more pronounced cardiac and vascular damage.
  • BPVSS can aid in risk stratification and management of hypertensive patients.
Abstract

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