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Updated: Dec 20, 2025
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Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
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[Vitamin D and osteoimmunology]
Yuichi Takashi1, Seiji Fukumoto1, Toshio Matsumoto1
1Fujii Memorial Institute of Medical Sciences, Tokushima University, Japan.
Clinical Calcium
|April 28, 2016
Summary
Vitamin D plays a key role in calcium and phosphate metabolism and influences immune function. Supplementation may help manage various diseases linked to vitamin D deficiency.
Area of Science:
- Endocrinology
- Immunology
- Nutritional Science
Context:
- Vitamin D is crucial for calcium and phosphate homeostasis.
- 1,25-dihydroxyvitamin D acts as a calciotropic hormone.
- Vitamin D metabolites influence cellular processes like proliferation and differentiation.
Purpose:
- To explore the multifaceted roles of vitamin D beyond mineral metabolism.
- To investigate the impact of vitamin D metabolites on the immune system.
- To review epidemiological evidence linking vitamin D status to disease prevalence.
Summary:
- Vitamin D is essential for maintaining calcium and phosphate balance.
- Its active metabolite, 1,25-dihydroxyvitamin D, regulates mineral metabolism and impacts cell behavior.
- Vitamin D metabolites modulate both innate and adaptive immunity.
- Deficiency is associated with autoimmune diseases, allergies, infections, and malignancies.
Impact:
- Highlights vitamin D's critical role in immune system regulation.
- Suggests potential therapeutic benefits of vitamin D supplementation for various health conditions.
- Underscores the importance of maintaining adequate vitamin D levels for overall health.
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