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Treatment of t(4;11) acute leukemia with aggressive multiagent chemotherapy. Preliminary results
T Hays1, H G Morse, V L Crouse
1Children's Hospital, Denver, CO 80218.
The American Journal of Pediatric Hematology/Oncology
|January 1, 1989
Abstract:
Acute leukemia patients with a 4;11 translocation have had a poor prognosis in the past, averaging 9 months survival from diagnosis. Three patients from The Children's Hospital of Denver were reported in 1982--all died. This report describes five additional patients who fared better. Aggressive treatment during induction and maintenance with intensive alternating non-cross-resistant chemotherapeutic agents may have contributed to the improved survival.