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Updated: Mar 22, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Assessment of Coronary Plaque Vulnerability with Optical Coherence Tomography
Shiro Uemura1, Tsunenari Soeda1, Yu Sugawara1
1First Department of Internal Medicine, Nara Medical University, Nara, Japan.
Unlabelled:
Several catheter-based imaging modalities have been developed over the past 2 decades for visualizing the morphological features of coronary atherosclerotic plaques that are susceptible to future development of serious cardiovascular events. Optical coherence tomography (OCT) is a new high-resolution intracoronary imaging modality based on near-infrared interferometry, and it has been shown to be able to identify various components of atheromatous plaques. In this review, we examine the histopathology of vulnerable plaques as a target for imaging technology, and discuss the evidence of OCT in identifying vulnerable atherosclerotic lesions in patients with coronary artery disease.
Key Words:
Coronary artery disease; Optical coherence tomography; Vulnerable plaque.
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