Related Experiment Video For Breast cancer
Updated: Mar 22, 2026

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Patient-Centered Communication for Discussing Oncotype DX Testing
Megan C Roberts1,2, Amy Bryson3, Morris Weinberger1,4
1a Department of Health Policy and Management , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
Abstract:
Oncotype DX testing (ODX), a tumor gene expression test, may improve breast cancer care, however, communicating results remains challenging. We identified patient-centered communication strategies/gaps for discussing ODX results. We applied a patient-centered communication framework to analyze qualitative interviews with oncologists about how they communicate about ODX with patients, using template analysis in Atlas.ti. Overall, providers discussed four patient-centered communication domains: exchanging information, assessing uncertainty, making decisions and cross-cutting themes. Providers did not report discussing emotional aspects of managing uncertainty, assessing decision-making preferences, and evaluating decisions. A patient-centered approach may be a model for communicating about tumor gene expression tests.
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