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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
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[Not Available].

Marie-germaine Bousser

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    Stroke incidence is rising globally despite lower mortality. Effective prevention, acute treatment, and rehabilitation are crucial, especially considering silent lesions contributing to cognitive decline and dementia.

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    Area of Science:

    • Neurology
    • Public Health
    • Epidemiology

    Context:

    • Global stroke burden is increasing despite reduced mortality.
    • Acute stroke treatment trials emphasize "time is brain."
    • Silent ischemic and hemorrhagic lesions are prevalent.

    Purpose:

    • To highlight the growing global burden of stroke.
    • To underscore the importance of stroke prevention, acute treatment, and rehabilitation.
    • To emphasize the link between silent cerebrovascular lesions and cognitive impairment.

    Summary:

    • Stroke mortality has decreased, but the overall global burden of stroke is rising.
    • Numerous clinical trials in acute ischemic, hemorrhagic, and subarachnoid stroke confirm "time is brain."
    • Magnetic Resonance Imaging (MRI) studies reveal frequent silent ischemic and hemorrhagic lesions, contributing to cognitive impairment and dementia.

    Impact:

    • Reinforces the critical need for enhanced stroke prevention strategies.
    • Underscores the significance of timely intervention in acute stroke.
    • Highlights the long-term cognitive consequences of cerebrovascular disease, including silent lesions.