Interactive high-quality visualization of color volume datasets using GPU-based refinements of segmentation data
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Updated: Mar 22, 2026

From Voxels to Knowledge: A Practical Guide to the Segmentation of Complex Electron Microscopy 3D-Data
Published on: August 13, 2014
Byeonghun Lee1, Koojoo Kwon2, Byeong-Seok Shin2
1Department of Research and Development, Zetta Imaging, Republic of Korea.
Abstract:
Data sets containing colored anatomical images of the human body, such as Visible Human or Visible Korean, show realistic internal organ structures. However, imperfect segmentations of these color images, which are typically generated manually or semi-automatically, produces poor-quality rendering results. We propose an interactive high-quality visualization method using GPU-based refinements to aid in the study of anatomical structures. In order to represent the boundaries of a region-of-interest (ROI) smoothly, we apply Gaussian filtering to the opacity values of the color volume. Morphological grayscale erosion operations are performed to reduce the region size, which is expanded by Gaussian filtering. Pseudo-coloring and color blending are also applied to the color volume in order to give more informative rendering results. We implement these operations on GPUs to speed up the refinements. As a result, our method delivered high-quality result images with smooth boundaries and provided considerably faster refinements. The speed of these refinements is sufficient to be used with interactive renderings as the ROI changes, especially compared to CPU-based methods. Moreover, the pseudo-coloring methods used presented anatomical structures clearly.
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