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Emerging Roles for the Unfolded Protein Response in the Developing Nervous System

Juliette D Godin1, Catherine Creppe2, Sophie Laguesse2

  • 1Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, University of Strasbourg, Illkirch, France.

Trends in Neurosciences
|May 1, 2016
PubMed
Summary

The unfolded protein response (UPR) pathway is crucial for central nervous system (CNS) development and neuron maintenance. Dysregulation of UPR is linked to neurodevelopmental disorders, offering therapeutic targets.

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