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Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
Published on: May 12, 2023
In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer
Archana Thakur1, Lawrence G Lum2
1Department of Oncology; Wayne State University, and Karmanos Cancer Institute ; Detroit, MI, USA.
Abstract:
Metastatic breast cancer remains an incurable disease. Most patients experience objective treatment responses associated with palliation of symptoms; however, progression inevitably occurs. Thus, there is an urgent need for innovative therapeutic strategies that may halt disease progression. Adoptive T-cell therapy is a potent and promising treatment option with the potential to harness the intrinsic antitumor power of the immune system and provide long-term immunity against cancer.
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