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Disulfiram's Anticancer Activity: Evidence and Mechanisms

Yang Jiao, Bethany N Hannafon, Wei-Qun Ding1

  • 1University of Oklahoma Health Sciences Center, 975 NE 10th Street, BRC 411A, Oklahoma City, OK 73104, USA.

Anti-Cancer Agents in Medicinal Chemistry
|May 5, 2016
PubMed
Summary

Disulfiram (DSF), an alcoholism drug, shows significant anticancer potential by targeting cancer stem cells and proteasome activity. Its established safety profile makes it a promising candidate for repurposing as a novel cancer therapeutic.

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