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Fish-T1K (Transcriptomes of 1,000 Fishes) Project: large-scale transcriptome data for fish evolution studies
Ying Sun1, Yu Huang2, Xiaofeng Li2
1State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275 China ; Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI, Shenzhen, 518083 China.
The Transcriptomes of 1,000 Fishes project is generating RNA-seq data for ray-finned fishes to advance evolutionary and functional studies. This initiative aims to fill a gap in
Area of Science:
- Evolutionary Biology
- Genomics
- Ichthyology
Background:
- Ray-finned fishes constitute over 50% of vertebrate species and hold significant evolutionary, ecological, and economic importance.
- These crucial species are currently underrepresented in 'omics studies, limiting comprehensive genetic and functional analyses.
- Advancing transcriptome data availability is essential for understanding gene expression and evolutionary trajectories in Actinopterygii.
Purpose of the Study:
- To establish the international "Transcriptomes of 1,000 Fishes" (Fish-T1K) project.
- To generate RNA-seq transcriptome sequences for a diverse range of 1,000 ray-finned fish species.
- To provide a foundational dataset for future functional and evolutionary research in fishes.
Main Methods:
- Implementation of the Fish-T1K project, an international collaborative effort.
- Generation of RNA-sequencing (RNA-seq) data for ray-finned fish transcriptomes.
- Bioinformatic processing and data curation of sequencing outputs.
Main Results:
- The initial phase of the Fish-T1K project has successfully generated transcriptomes for over 180 ray-finned fishes.
- This dataset encompasses 142 distinct species, spanning 51 orders and 109 families.
- The project has laid the groundwork for a comprehensive genomic resource for ray-finned fishes.
Conclusions:
- The Fish-T1K project is significantly enhancing the genomic resources available for ray-finned fishes.
- The generated transcriptome data will facilitate deeper insights into gene expression, functional genomics, and evolutionary patterns.
- This initiative addresses a critical gap in 'omics research for a highly diverse and significant vertebrate group.
