Related Experiment Video
Updated: Feb 16, 2026
08:34
Cryogenic Liquid Jets for High Repetition Rate Discovery Science
Published on: May 9, 2020
3.5K
Fundamentals of Neurogastroenterology: Basic Science
Stephen Vanner1, Beverley Greenwood-Van Meerveld2, Gary Mawe3
1Gastrointestinal Diseases Research Unit, Kingston General Hospital, Kingston, Ontario, Canada.
Gastroenterology
|May 5, 2016
Summary
This review explores neurogastroenterology fundamentals for functional GI disorders (FGIDs). Advances in the enteric nervous system, pain, and stress pathways offer new therapeutic targets for FGIDs.
Area of Science:
- Neurogastroenterology
- Gastrointestinal Physiology
- Immunology
Background:
- Functional gastrointestinal disorders (FGIDs) are complex conditions.
- Understanding the pathophysiology of FGIDs is crucial for effective treatment.
- Recent evidence implicates the microbiome, diet, and immune activation in FGIDs.
Purpose of the Study:
- To review the fundamentals of neurogastroenterology relevant to FGID pathophysiology.
- To highlight recent advances in understanding the enteric nervous system, sensory physiology, and stress signaling.
- To discuss the role of neuroimmune signaling and intestinal barrier function in FGIDs.
Main Methods:
- Consensus document preparation by an international committee of experts.
- Abbreviated review of key findings for broader accessibility.
- Emphasis on recent scientific literature and evidence.
Main Results:
- Recent advances in understanding the enteric nervous system.
- New insights into sensory physiology and pain mechanisms in FGIDs.
- Exploration of stress signaling pathways, neuroimmune interactions, and intestinal barrier function.
Conclusions:
- Advances in neurogastroenterology provide novel targets for FGID treatment.
- The microbiome, diet, and mucosal immunity are key factors in FGID pathophysiology.
- Further research into these areas holds promise for future therapeutic strategies.
Related Concept Videos
01:23Fundamental Theorem of Calculus I
109
Solving problems involving definite integrals requires a systematic approach that ensures clarity and efficiency. The first step is understanding the problem by identifying the calculated quantity, whether it involves accumulation, area, or a physical concept like force or probability. It is essential to recognize given conditions, such as the range of integration and any constraints that may affect the solution. Before computing, key properties of definite integrals should be analyzed to...
109
01:30Fundamental Theorem of Algebra
300
The Fundamental Theorem of Algebra is central to the study of polynomial equations, asserting that every non-constant polynomial with complex coefficients has at least one complex zero. This means that a polynomial of degree n ≥ 1, written as: with an ≠ 0, has at least one solution in the complex number system. Since the set of real numbers is a subset of complex numbers, this theorem applies equally to polynomials with real coefficients.Building on this result, the...
300
01:14Fundamental Attribution Error
13.8K
According to some social psychologists, people tend to overemphasize internal factors as explanations—or attributions—for the behavior of other people. They tend to assume that the behavior of another person is a trait of that person, and to underestimate the power of the situation on the behavior of others. They tend to fail to recognize when the behavior of another is due to situational variables, and thus to the person’s state. This erroneous assumption is...
13.8K
01:13Psychology as a Science
4.0K
Psychology, as a scientific discipline, aims to understand the mind and behavior through rigorous and systematic methods. The foundation of psychological research is evidence-based, relying heavily on the scientific method to derive and validate knowledge. This structured approach ensures that findings are reliable, valid, and applicable to broader contexts.
The scientific method in psychology involves six critical steps: making observations, formulating hypotheses, conducting tests, analyzing...
The scientific method in psychology involves six critical steps: making observations, formulating hypotheses, conducting tests, analyzing...
4.0K
01:28Electrocardiogram Fundamentals
1.6K
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
1.6K
01:27Fundamentals of Nursing Process I
9.1K
The nursing process is the core of practice for every registered nurse to deliver holistic, patient-focused care. The following are the five steps in the nursing process.
9.1K