Related Experiment Video
Updated: Mar 21, 2026
Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Seasonal Incidence of Emergent Coronary Artery Bypass Grafting Surgery
Jimmy T Efird1, William Fenner Griffin2, Stephen W Davies3
11. East Carolina Heart Institute, Department of Cardiovascular Sciences, East Carolina University, Greenville, NC 2.Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC 3. The College of Nursing, East Carolina University, Greenville, NC. jimmy.efird@stanfordalumni.org.
Insights
Emergent coronary artery bypass grafting (CABG) surgery incidence shows seasonal variation, peaking in late winter. This finding aids hospital resource planning and offers insights into coronary artery disease etiology.
Area of Science:
- Cardiovascular Surgery
- Epidemiology
- Public Health
Background:
- Severe coronary artery disease (CAD) refractory to traditional management necessitates emergent coronary artery bypass grafting (CABG).
- Understanding temporal patterns in emergent CABG incidence is crucial for healthcare management and etiological research.
Purpose of the Study:
- To investigate potential seasonal variations in the occurrence of emergent CABG.
- To test the hypothesis of a seasonal pattern in severe CAD requiring urgent surgical intervention.
Main Methods:
- Analysis of 270 emergent CABG cases over 5939 days at a cardiovascular institute.
- Application of a sinusoidal logistic regression model to identify cyclic trends in operative data.
Main Results:
- A statistically significant peak in the risk for emergent CABG was identified in late winter (day 66).
- Odds ratios indicated increased risk in the 1, 2, and 3-month windows surrounding the winter peak, with significant P-values for the 2-month window.
Conclusions:
- The study suggests a seasonal variation in the incidence of severe CAD requiring emergent CABG.
- Findings are valuable for optimizing hospital resource allocation and staff scheduling.
- Identified seasonal patterns may provide etiological insights into CAD, potentially guiding future therapeutic strategies.
Background:
Emergent coronary artery bypass grafting (CABG) surgery is often required in the case of severe coronary artery disease, which is refractory to traditional management. The objective of our study was to test the hypothesis that there is seasonal variation in the incidence of emergent CABG.
Methods:
A sinusoidal logistic regression model was used to analyze operative data at our cardiovascular institute of 270 cases spanning 5939 calendar days.
Results:
A cyclic peak risk for emergent CABG was observed for late winter (calendar day 66; P = .036). The odds ratios for the 1-, 2- and 3-month window surrounding this peak were 1.8 (95% CI = 0.94-3.5, P = .072), 1.6 (95% CI = 1.06-2.5, P = .024) and 1.4 (95% CI = 0.9-1.8, P = .066), respectively.
Conclusion:
Our results suggest that a seasonal variation may exist in the incidence of patients presenting with severe coronary artery disease requiring emergent CABG. This information is useful in the scheduling of hospital resources and staff. It also provides important etiology clues underlying coronary artery disease that may lead to future interventions or targeted therapies.
Related Concept Videos
01:30Introduction Cardiac Emergencies
01:30Acute Coronary Syndrome I: Introduction
01:27Coronary Artery Disease V: Interprofessional Care
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
01:28Acute Coronary Syndrome IV: Interprofessional Care