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An Aggressive Retroperitoneal Fibromatosis
Zoran Campara1, Aleksandar Spasic1, Predrag Aleksic1
1Department of Urology, Military Medical Academy, Belgrade, Serbia.
Summary
Aggressive fibromatosis (AF) is a rare tumor. Complete surgical removal is the best treatment for aggressive fibromatosis, preventing recurrence.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Aggressive fibromatosis (AF) comprises heterogeneous mesenchymal tumors characterized by local infiltration and recurrence.
- Clinical presentation is often dictated by ureteral or intestinal obstruction.
- Diagnosis relies on integrated clinical, radiological, and histological assessments.
Observation:
- A 35-year-old male presented with retroperitoneal fibromatosis.
- Symptoms included frequent urination, pressure, and pain.
- CT revealed a 70mm bladder wall tumor infiltrating the abdominal musculature.
Findings:
- Endoscopic biopsy confirmed a proliferative fibromatosis lesion.
- Complete surgical resection was performed.
- The patient remained recurrence-free at 36 months post-surgery.
Implications:
- Complete tumor resection is the definitive treatment for primary and recurrent aggressive fibromatosis.
- Early diagnosis and surgical intervention are crucial for favorable outcomes.
- This case highlights successful management of retroperitoneal fibromatosis.

