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Targeted temperature management in emergency medicine: current perspectives
Benton R Hunter1, Timothy J Ellender2
1Department of Emergency Medicine, Indiana University School of Medicine, Indiana University, Indianapolis, IN, USA.
Open Access Emergency Medicine : OAEM
|May 6, 2016
Summary
Therapeutic hypothermia (TH) improves neurologic recovery after cardiac arrest. Recent evidence guides optimal use of TH, also known as targeted temperature management, in emergency medicine settings for cardiac arrest survivors.
Area of Science:
- Emergency Medicine
- Cardiology
- Neurology
Background:
- Landmark 2002 trials established therapeutic hypothermia (TH) benefits for cardiac arrest survivors.
- TH use expanded beyond initial indications (ventricular tachycardia/fibrillation) to broader cardiac arrest populations.
- Recent research focuses on optimizing TH implementation in cardiac arrest management.
Purpose of the Study:
- To review early and recent evidence on therapeutic hypothermia (TH) or targeted temperature management (TTM) in cardiac arrest.
- To provide evidence-based recommendations for TTM/TH in diverse emergency medicine scenarios.
Main Methods:
- Review of landmark trials and recent clinical evidence.
- Synthesis of data regarding the application of TH/TTM in cardiac arrest patients.
- Development of practical suggestions for emergency medicine settings.
Main Results:
- Early evidence demonstrated improved neurologic outcomes with TH post-cardiac arrest.
- Recent trials investigate optimal timing, methods, and temperature targets for TH/TTM.
- Varied application of TH/TTM exists, necessitating updated guidance.
Conclusions:
- Therapeutic hypothermia/targeted temperature management remains crucial for improving outcomes after cardiac arrest.
- Evidence-based guidelines are essential for consistent and effective application of TH/TTM.
- Further research may refine TTM protocols for specific patient subgroups and arrest rhythms.
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