Mechanisms of the Maternal Exposome and Implications for Health Outcomes
Michelle L Wright1, Angela R Starkweather, Timothy P York
1University of Connecticut, School of Nursing, Storrs, Connecticut (Dr Starkweather), Yale University, School of Nursing, West Haven, Connecticut (Dr Wright); and Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human and Molecular Genetics, and Department of Obstetrics and Gynecology, Virginia Commonwealth University School of Medicine, Richmond (Dr York).
Abstract:
It is well established that the environment contributes to health. However, few studies have evaluated environmental exposures in women that may influence future health of their offspring. Knowledge gained may inform nursing how to better advocate for patients and families, and provide individualized interventions and education. Therefore, a more comprehensive investigation of the maternal exposome to uncover mechanistic insight into complex disease in offspring is warranted. To advance understanding of biologic mechanisms that contribute to high-risk birth outcomes and offspring predisposition to disease, it will be necessary to measure a range of exposures and biomarkers before and during pregnancy.
More Related Videos
06:39Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
09:09Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using PolyI:C to Study Susceptibility and Resilience in Offspring
Published on: August 17, 2022
Related Concept Videos
Development of the Oral Microbiota
Gene-Environment Interactions
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Teratogenicity
Epigenetic Regulation
X-chromosome...
