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Related Concept Videos

The Functions of the Skeletal System01:22

The Functions of the Skeletal System

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The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
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Hypodermis01:02

Hypodermis

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The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
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Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

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Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts—...
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Bone Structure01:55

Bone Structure

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Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
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Loose Connective Tissue01:26

Loose Connective Tissue

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Loose connective tissue is found between many organs. Its main function is to absorb shock and bind tissues together. It also allows water, salts, and various nutrients to diffuse into cells that are embedded in it or present in adjacent tissues.
Adipose Tissue
Adipose tissue consists primarily of fat storage cells called adipocytes and little extracellular matrix. A large number of capillaries present within adipose tissue allow rapid mobilization of lipid molecules. White adipose tissue is...
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Bone Cells and Tissue01:30

Bone Cells and Tissue

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Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
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The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the...
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Related Experiment Video

Updated: Mar 21, 2026

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice
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Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

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Brown adipose tissue and bone.

M E Lidell1, S Enerbäck1

  • 1Department of Medical and Clinical Genetics, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg , Gothenburg, Sweden.

International Journal of Obesity Supplements
|May 7, 2016
PubMed
Summary

Brown adipose tissue (BAT), which generates heat from stored energy, is found in many adults and linked to better metabolic health. Emerging research suggests BAT may also play a role in bone metabolism and growth.

Area of Science:

  • Metabolic physiology
  • Endocrinology
  • Bone biology

Background:

  • Brown adipose tissue (BAT) converts stored energy (triglycerides) into heat.
  • Metabolically active BAT is prevalent in adult humans and associated with favorable metabolic status.
  • BAT is a therapeutic target for obesity and type 2 diabetes due to its thermogenic properties.

Purpose of the Study:

  • To provide an overview of the current brown adipose tissue research landscape.
  • To summarize recent findings on the role of BAT in bone metabolism.
  • To discuss the potential of BAT as a modulator of bone anabolism.

Main Methods:

  • Literature review of recent studies on brown adipose tissue.
  • Analysis of correlations between BAT activity/volume and metabolic/bone parameters.

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Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
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Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT

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Identification and Dissection of Diverse Mouse Adipose Depots
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Identification and Dissection of Diverse Mouse Adipose Depots

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Related Experiment Videos

Last Updated: Mar 21, 2026

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice
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Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
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  • Synthesis of evidence regarding BAT's influence on bone metabolism.

    • Main Results:

    • BAT activity correlates with improved metabolic health.
    • Increased BAT volume is linked to larger bone cross-sectional area and higher bone mineral density.
    • These findings suggest a potential anabolic role for BAT in bone.

    Conclusions:

    • Brown adipose tissue is a promising target for metabolic disease therapies.
    • BAT may actively influence bone metabolism, potentially stimulating bone anabolism.
    • Further research is warranted to elucidate the mechanisms of BAT's effect on bone health.