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Benign hormone-secreting adenoma within a larger adrenocortical mass showing intensely increased activity on 18F-FDG
Georgios Z Papadakis1, Corina Millo2, Constantine A Stratakis3
1Radiology and Imaging Sciences, Warren Grant Magnuson Clinical Center (CC), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
Abstract:
Adrenal adenomas usually show 18F-FDG activity less than that of the liver parenchyma. However, lipid-poor and hormone-secreting adenomas have been reported to show mild 18F-FDG avidity. We report on a 51-year-old female with clinical symptoms of hypercortisolemia and a large right adrenal mass detected on CT. Post-contrast CT images showed an enhancing focus in the lower pole of the mass, with corresponding markedly increased activity on 18F-FDG PET/CT. Right adrenalectomy was performed and histology revealed a benign adenoma, indicating that functioning benign adenomas can show intensely increased metabolic activity on 18F-FDG mimicking malignancy.
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