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Published on: April 13, 2018
Normal Variants and Effects of Aging on the Gastrointestinal Tract
Rakesh Kumar1, Jaseena Elikkottil1, Suhas Singla1
1Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India.
Aging causes changes in the gastrointestinal tract visible on PET and PET/CT scans. Understanding these normal variants and artifacts is crucial to avoid misdiagnosis in elderly patients.
Area of Science:
- Medical Imaging
- Geriatrics
- Gastroenterology
Background:
- The elderly population is growing, increasing demand for advanced imaging like Positron Emission Tomography (PET) and PET/Computed Tomography (PET/CT).
- PET and PET/CT imaging reveal numerous variants and artifacts that can lead to misinterpretation, particularly in older adults.
- Accurate interpretation requires distinguishing true pathology from normal age-related changes.
Purpose of the Study:
- To review normal age-related variants and artifacts in the gastrointestinal tract as seen on PET and PET/CT imaging.
- To provide clinicians with essential knowledge for differentiating normal aging changes from pathological findings in the elderly gastrointestinal system.
Main Methods:
- Literature review of studies focusing on age-related changes in gastrointestinal imaging.
- Analysis of common variants and artifacts in PET and PET/CT scans of the elderly gastrointestinal tract.
Main Results:
- Identified specific structural and functional changes in the aging gastrointestinal tract that mimic disease on PET/CT.
- Detailed common artifacts, such as partial volume effects and physiological variations, that can lead to false positives.
Conclusions:
- Familiarity with age-related gastrointestinal variants and artifacts on PET and PET/CT is essential for accurate diagnosis in the elderly.
- This knowledge aids in reducing unnecessary follow-up procedures and patient anxiety by preventing misinterpretation of imaging findings.
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