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Updated: Mar 21, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Impact of PET/CT-Based Radiation Therapy Planning in Gastrointestinal Malignancies
Chiaojung Jillian Tsai1, Prajnan Das
1Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 97, Houston, TX 77030, USA.
Abstract:
Many studies have explored the use of (18)F-flurodeoxyglucose (FDG-PET) with CT for radiation therapy planning. The addition of PET/CT could improve tumor volume delineation, reduce geographic misses, and decrease treatment-related toxicity. For cancers of the gastrointestinal tract, the potential benefit of FDG-PET in radiation therapy management is less frequently studied. This article reviews the literature concerning PET/CT in radiation treatment planning. PET/CT appears to have an impact on tumor volume definition. More studies are needed to determine the impact of PET/CT-based radiation therapy on local control, patterns of failure, and treatment-related toxicity.
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