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Updated: Mar 21, 2026
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
A Multimodality Imaging Review of Malignant Pleural Mesothelioma Response Assessment
Anna K Nowak1, Roslyn J Francis1, Sharyn I Katz2
1School of Medicine and Pharmacology, University of Western Australia, 35 Stirling Highway, Nedlands, Perth 6009, Western Australia, Australia; Department of Medical Oncology, Sir Charles Gairdner Hospital, Verdun Street, Nedlands, Perth 6009, Western Australia, Australia.
Abstract:
Assessment of response is important to interpret early phase clinical trial results and to guide individual patient management. In malignant pleural mesothelioma (MPM), the circumferential growth pattern of the disease, the presence of pleural effusion and atelectasis, and the common use of pleurodesis make this a challenging task for imaging specialists and clinicians. This article reviews the current evidence for radiological and positron emission tomography (PET) response assessment in MPM, and the pitfalls and challenges in its application. Current research and future directions in radiological and PET response are discussed, including the use of novel radiotracers.
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