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The Use of PET in Radiation Therapy for Lymphoma
John P Plastaras1, Geoffrey Geiger1, Rodolfo Perini2
1Department of Radiation Oncology, Perelman Center for Advanced Medicine, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
Abstract:
Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) and computed tomography (CT) has essentially replaced CT alone for staging of lymphomas. FDG-PET has been incorporated into the revised response criteria, but response adapted strategies are still being evaluated. The role of FDG-PET/CT in radiation treatment planning is still being developed. It is unclear how to use FDG-PET/CT to determine whether to give consolidative radiation, where to radiate, and what dose. Ongoing efforts are underway to use early interim FDG-PET/CT to limit therapy in good prognosis patients. A multidisciplinary team is important in the management of patients with lymphoma, leading to individualized treatment plans and better outcomes.
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