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Updated: Mar 21, 2026

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Positron Emission Tomography in Head and Neck Squamous Cell Carcinoma of Unknown Primary
Kimberly J Kinder1, Pierre Lavertu1, Min Yao2
1Department of Otolaryngology-Head and Neck Surgery, University Hospitals Case Medical Center, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
Abstract:
This article summarizes selected published studies on the use of FDG-PET and PET/CT in the workup of head and neck carcinoma of unknown primary (HNCUP). It shows that PET is a useful imaging modality in identification of the occult primary tumor and discovery of distant metastases. The results of PET often lead to a change in management in these patients. The limitations of PET in HNCUP are also discussed.
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