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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

8.0K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Related Experiment Video

Updated: Mar 21, 2026

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm
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Advances in Attenuation Correction Techniques in PET.

Habib Zaidi1, Marie-Louise Montandon1, Abass Alavi2

  • 1Division of Nuclear Medicine, Geneva University Hospital, CH-1211 Geneva 4, Switzerland.

PET Clinics
|May 10, 2016
PubMed
Summary
This summary is machine-generated.

Photon attenuation significantly impacts Positron Emission Tomography (PET) image quality. This review details advanced algorithms for accurate attenuation mapping and compensation in whole-body PET imaging.

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Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
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Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Biophysics

Background:

  • Positron Emission Tomography (PET) has transitioned from research to clinical practice.
  • Advances in PET scanner technology and quantitative protocols are crucial.
  • Photon attenuation is a primary challenge for PET image quality and accuracy.

Purpose of the Study:

  • To present the physical and methodological basis of photon attenuation in PET.
  • To summarize current algorithms for attenuation map generation.
  • To discuss future trends and challenges in attenuation compensation.

Main Methods:

  • Review of physical principles of photon attenuation in biological tissues.
  • Summary of state-of-the-art algorithms for deriving attenuation maps.
  • Analysis of techniques for accurate attenuation compensation in PET data.

Main Results:

  • Photon attenuation is a critical factor degrading PET image quality.
  • Various strategies exist for creating attenuation maps for correction.
  • Advanced algorithms aim for precise attenuation compensation in whole-body PET.

Conclusions:

  • Accurate attenuation compensation is vital for quantitative PET imaging.
  • Ongoing research focuses on improving attenuation correction methods.
  • Future work should address remaining challenges in PET data analysis.