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MRI and PET in Mouse Models of Myocardial Infarction
Published on: December 19, 2013
New Concepts for Assessing Global Organ Function and Disease Activity Based on Combined PET and Structural Imaging
Sandip Basu1, Habib Zaidi2, Abass Alavi1
1Department of Radiology, Division of Nuclear Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 1 Donner Building, Philadelphia, PA 19104-4283, USA.
Abstract:
This review is intended to discuss ways in which global and regional organ function may be assessed by using modern tomographic imaging methods. In addition, we discuss using (18)F-Fluorodeoxyglucose (FDG)-PET to monitor treatment response in various tumors as well as quantification of tumor burden in the entire body. We have selected FDG as a model that can also be adopted for other PET radiotracers. The merits of advanced quantitative measures for disease activity assessment in cancer and other disorders will also be addressed.
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