Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Surveys02:16

Surveys

17.2K
Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
17.2K
Nominal Level of Measurement00:56

Nominal Level of Measurement

41.7K
The way a set of data is measured is called its level of measurement. Correct statistical procedures depend on a researcher being familiar with levels of measurement. Not every statistical operation can be used with every set of data. For analysis, data are classified into four levels of measurement—nominal, ordinal, interval, and ratio.
The data that cannot be measured but can be grouped into categories fall under the nominal level of measurement. Data that is measured using a nominal...
41.7K
Response Surface Methodology01:16

Response Surface Methodology

789
Response Surface Methodology (RSM) is a collection of statistical and mathematical techniques used to develop, improve, and optimize processes. It is particularly valuable when many input variables or factors potentially influence a response variable.
The process of RSM involves several key steps:
789
Ordinal Level of Measurement00:55

Ordinal Level of Measurement

36.8K
The way a set of data is measured is called its level of measurement. Correct statistical procedures depend on a researcher being familiar with levels of measurement. For analysis, data are classified into four levels of measurement—nominal, ordinal, interval, and ratio.
Data measured using an ordinal scale are similar to nominal scale data, but there is one major difference. The ordinal scale data can be ordered. An example of ordinal scale data is a list of the top five national parks...
36.8K
How Data are Classified: Numerical Data00:59

How Data are Classified: Numerical Data

40.6K
Data that are countable or measurable in specific units are called numerical or quantitative data. Quantitative data are always numbers. Quantitative data are the result of counting or measuring the attributes of a population. Amount of money, pulse rate, weight, number of people living in a town, and number of students who opt for statistics are examples of quantitative data.
Quantitative data may be either discrete or continuous. All quantitative data that take on only specific numerical...
40.6K
Ratio Level of Measurement00:54

Ratio Level of Measurement

22.2K
The way a set of data is measured is called its level of measurement. Correct statistical procedures depend on a researcher being familiar with levels of measurement. For analysis, data are classified into four levels of measurement—nominal, ordinal, interval, and ratio.
A set of data measured using the ratio scale takes care of the ratio problem and provides complete information. Ratio scale data are like interval scale data, except they have a zero point and ratios can be calculated....
22.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Total Body PET.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
Same author

Validation of a Deep-Learning Coregistration Framework for Long-Axial-Field-of-View PET/CT Using Low-Radiation-Exposure Protocols Across Various Tracers.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Developing Topics.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Delayed [<sup>89</sup>Zr]Zr-<i>N</i>-Succinyldesferal-Trastuzumab Imaging Enabled by Long-Axial-Field-of-View PET/CT.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025
Same author

Influence of Ultra-Low-Dose CT on PET Image Quantification and Visual Assessment.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025
Same author

Imaging Proinflammatory Microglia in Parkinson Disease Using [<sup>11</sup>C]SMW139 PET: A Multicenter Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025
Same journal

<sup>18</sup>F-fluorodeoxyglucose PET in Major Psychiatric Disorders.

PET clinics·2026
Same journal

Five Decades of [18F]Fluorodeoxyglucose-PET in Neuropsychiatric Disorders: From Brain Metabolism to Precision Functional Imaging.

PET clinics·2026
Same journal

Brain [18F]FDG PET in Subjective Cognitive Complaints: From Diagnostic Gap to Neurobiological Insight.

PET clinics·2026
Same journal

FDG PET in Movement Disorders and Parkinsonian Syndromes.

PET clinics·2026
Same journal

Brain [18F]FDG PET in Encephalitis and Postinfectious Neurocognitive Syndromes.

PET clinics·2026
Same journal

Theranostics in Nuclear Medicine: Historical, Regulatory, and Evidence Context for the Practicing Nuclear Medicine Physician.

PET clinics·2026
See all related articles

Related Experiment Video

Updated: Mar 21, 2026

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents
09:43

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents

Published on: August 10, 2014

47.2K

Quantitative Issues in Response Measurement by PET.

Adriaan A Lammertsma1, Ronald Boellaard1, Otto S Hoekstra1

  • 1Department of Nuclear Medicine and PET Research, VU University Medical Center, Amsterdam, The Netherlands.

PET Clinics
|May 10, 2016
PubMed
Summary
This summary is machine-generated.

Accurate positron emission tomography (PET) quantification is crucial for monitoring cancer therapy response. This review details instrumentation and analysis challenges impacting PET quantification across all tracers, focusing on FDG.

Keywords:
FDGPETQuantificationResponse monitoringTracer kinetic modeling

More Related Videos

The Rodent Psychomotor Vigilance Test rPVT: A Method for Assessing Neurobehavioral Performance in Rats and Mice
07:47

The Rodent Psychomotor Vigilance Test rPVT: A Method for Assessing Neurobehavioral Performance in Rats and Mice

Published on: December 29, 2016

12.9K
Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses
07:59

Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses

Published on: September 19, 2011

13.2K

Related Experiment Videos

Last Updated: Mar 21, 2026

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents
09:43

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents

Published on: August 10, 2014

47.2K
The Rodent Psychomotor Vigilance Test rPVT: A Method for Assessing Neurobehavioral Performance in Rats and Mice
07:47

The Rodent Psychomotor Vigilance Test rPVT: A Method for Assessing Neurobehavioral Performance in Rats and Mice

Published on: December 29, 2016

12.9K
Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses
07:59

Using a Comparative Species Approach to Investigate the Neurobiology of Paternal Responses

Published on: September 19, 2011

13.2K

Area of Science:

  • Nuclear medicine
  • Medical imaging
  • Oncology

Background:

  • Effective monitoring of anticancer therapy response is essential for patient outcomes.
  • Quantitative positron emission tomography (PET) provides valuable insights into treatment efficacy.
  • Standardized quantification methods are needed to ensure reliable assessment of therapeutic response.

Purpose of the Study:

  • To review key instrumentation and analysis issues affecting quantitative PET imaging.
  • To highlight challenges in data acquisition, image reconstruction, and image analysis for PET.
  • To discuss the impact of these issues on the accuracy of PET quantification in oncology.

Main Methods:

  • Review of instrumentation and analysis factors influencing PET quantification.
  • Categorization of issues into data acquisition, image reconstruction, image analysis, and data analysis.
  • Focus on 18F-fluorodeoxyglucose (FDG) but applicable to all PET tracers.

Main Results:

  • Identified several critical instrumentation and analysis steps impacting PET quantification accuracy.
  • Detailed specific challenges within data acquisition, reconstruction, and analysis phases.
  • Emphasized the broad applicability of these quantification issues across various PET tracers.

Conclusions:

  • Addressing instrumentation and analysis issues is vital for reliable (semi)quantitative PET in cancer therapy monitoring.
  • Standardization of PET quantification methods is necessary for consistent and accurate assessment of treatment response.
  • The principles discussed are fundamental for advancing the clinical utility of PET imaging in oncology.