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Atrial Electromechanical Properties in Inflammatory Bowel Disease
Tolga Han Efe1, Tolga Cimen2, Ahmet Goktug Ertem3
1Department of Cardiology, Diskapi Yildirim Beyazit Education and Training Hospital, Ankara, Turkey. medisay@gmail.com.
Inflammatory bowel disease (IBD) patients show prolonged atrial electromechanical delay (EMD), indicating a higher risk for atrial fibrillation (AF). This suggests chronic inflammation impacts heart electrical activity, potentially aiding AF risk prediction in IBD.
Area of Science:
- Cardiology
- Gastroenterology
- Electrophysiology
Background:
- Inflammation is linked to atrial fibrillation (AF) initiation and progression.
- Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are chronic systemic inflammatory conditions.
- Atrial electromechanical delay (EMD) is an early marker for AF.
Purpose of the Study:
- To assess atrial electromechanical properties in patients with IBD.
- To investigate the relationship between IBD activity and atrial electrophysiology.
Main Methods:
- Fifty-two IBD patients (25 active, 27 remission) and 26 healthy controls were studied.
- Atrial electromechanical properties were measured using transthoracic echocardiography, tissue Doppler imaging, and ECG.
- Interatrial, left intraatrial, and right intraatrial EMD were calculated.
Main Results:
- IBD patients in the active phase exhibited significantly prolonged left/right intraatrial and interatrial EMD compared to those in remission and healthy controls.
- Patients with IBD in remission also showed higher EMD values than healthy controls.
- No significant differences in EMD were found between UC and CD patients.
Conclusions:
- Atrial electromechanical conduction is impaired in IBD patients, likely due to chronic inflammation-induced atrial tissue changes.
- Prolonged atrial EMD in IBD suggests a potential risk factor for developing AF.
- Atrial EMD measurement may aid in predicting AF risk in the IBD population.
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