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Pseudotumor cerebri in systemic lupus erythematosus
The Journal of Rheumatology
|January 1, 1989
Summary
Pseudotumor cerebri, a condition of raised intracranial pressure, can occur with systemic lupus erythematosus (SLE). Corticosteroid therapy effectively treated three women with SLE-associated pseudotumor cerebri and papilledema.
Area of Science:
- Neurology
- Ophthalmology
- Rheumatology
Background:
- Pseudotumor cerebri (idiopathic intracranial hypertension) is characterized by elevated intracranial pressure without mass lesions or hydrocephalus.
- Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse clinical manifestations.
- Neurologic manifestations of SLE are varied, with papilledema being an infrequently encountered sign.
Observation:
- This study reports on three female patients diagnosed with systemic lupus erythematosus (SLE).
- All three patients presented with symptoms indicative of pseudotumor cerebri.
- The patients also exhibited papilledema, a key neuroophthalmological sign.
Findings:
- The three women with SLE and pseudotumor cerebri demonstrated a positive response to treatment.
- Corticosteroid therapy was the primary intervention used.
- The neuroophthalmological symptoms, including papilledema, resolved with treatment.
Implications:
- Corticosteroids may be an effective treatment for pseudotumor cerebri associated with SLE.
- This highlights the importance of neuroophthalmological monitoring in SLE patients.
- Early diagnosis and treatment can improve outcomes for SLE patients with neurological complications.