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Meatal Occlusive Disease in Adult Males: Are There Any Clinical Variations?

Divakar Dalela1, Piyush Gupta, Disha Dalela

  • 1Department of Urology, King George Medical University, Lucknow, India.

Urologia Internationalis
|May 11, 2016
PubMed
Abstract

Insights

Meatal occlusive disease (MOD) in adult males presents as two distinct types: meatal synechia and meatal stenosis. Meatal stenosis shows a higher recurrence rate, indicating different therapeutic outcomes for each type of MOD.

Area of Science:

  • Urology
  • Andrology
  • Medical Research

Background:

  • Meatal occlusive disease (MOD) is a condition affecting adult males, characterized by obstruction of the urethral meatus.
  • Understanding the distinct types of MOD is crucial for effective clinical management and prognosis.

Purpose of the Study:

  • To document the types of meatal occlusive disease (MOD) in adult males.
  • To analyze the clinical presentation, management strategies, and prognosis associated with different MOD types.

Main Methods:

  • Eighty-six adult males with MOD were classified into two groups: meatal synechia (Group 1) and meatal stenosis (Group 2).
  • All patients underwent meatal dilatation followed by a 3-month self-dilatation regimen with topical clobetasol.
  • Outcomes assessed included discomfort, flow rate improvement, International Prostate Symptom Score (IPSS), and recurrence rates.

Main Results:

  • Meatal synechia (28 patients) showed significantly less discomfort during self-dilatation compared to meatal stenosis (48 patients).
  • Both groups demonstrated improvement in IPSS and peak flow rate, with a mean follow-up of 26.8 months.
  • No recurrence was observed in the meatal synechia group with dilation alone, whereas the meatal stenosis group had a 62.8% recurrence rate.

Conclusions:

  • Meatal occlusive disease in adult males comprises two separate clinical entities: meatal synechia and meatal stenosis.
  • These distinct types of MOD exhibit different therapeutic outcomes, with meatal stenosis having a poorer prognosis due to higher recurrence.

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