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Updated: Mar 21, 2026

Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
Merkel cell carcinoma: a review
Christian W Oram1, Cynthia L Bartus1, Stephen M Purcell1
1Lehigh Valley Health Network/Philadelphia College of Osteopathic Medicine Dermatology Program, Pennsylvania, USA.
Abstract:
Merkel cell carcinoma (MCC) is a rare neuroendocrine tumor of unknown origin that usually presents in the elderly population. A novel polyomavirus has been associated with a large percentage of tumors. Immune response plays an important role in pathogenesis of MCC. This article reviews the history, pathogenesis, presentation, and treatment of MCC. Future treatments also are discussed briefly.
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