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Do African-American men need separate prostate cancer screening guidelines?
Divya Shenoy1, Satyaseelan Packianathan2, Allen M Chen3
1University of Mississippi Medical School, Jackson, MS, USA.
BMC Urology
|May 12, 2016
Summary
African American men have a higher incidence and mortality rate for prostate cancer. Separate screening guidelines are crucial to address these disparities and improve outcomes for this population.
Area of Science:
- Oncology
- Public Health
- Health Disparities
Background:
- Current United States Preventative Services Task Force guidelines recommend against prostate cancer screening for all men.
- African American men experience a 60% higher incidence and 2-3 times greater mortality rate from prostate cancer compared to Caucasian men.
- The existing guidelines are based on studies with limited African American representation.
Purpose of the Study:
- To advocate for separate prostate cancer screening guidelines for African American men.
- To reduce the disproportionate burden of prostate cancer in African American men.
Main Methods:
- A PubMed literature search was conducted.
- Keywords included: African American, Prostate cancer, Outcomes, Molecular markers, Prostate-specific Antigen velocity, and PSA density.
- Data was gathered to support the hypothesis for distinct screening recommendations.
Main Results:
- Significant differences exist in prostate cancer incidence, outcomes, clinical course, serum PSA levels, genetic factors, and social barriers between Caucasian and African American men.
- The studies underpinning the USPSTF guidelines had minimal inclusion of African American participants.
- One study lacked demographic data and primarily used European participants.
Conclusions:
- Separate prostate cancer screening guidelines are essential for African American men.
- Implementing tailored guidelines can help save lives within this demographic.
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