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Baiting for Cancer: Using the Zebrafish as a Model in Liver and Pancreatic Cancer
Katie L Hwang1,2, Wolfram Goessling3,4,5,6
1Harvard Medical School, Medical Scientist Training Program, Boston, MA, USA.
Advances in Experimental Medicine and Biology
|May 12, 2016
Abstract:
Liver and pancreatic cancers are amongst the leading causes of cancer death. In recent years, genetic and chemical approaches in zebrafish have elucidated cellular and molecular mechanisms of liver and pancreatic cancer formation and progression. In this chapter, we review the recent approaches and advances in the field to study both hepatocellular carcinomas and pancreatic cancer.
Keywords:
Liver cancerLiver developmentMutationsPancreas cancerPancreas developmentTransgenesisZebrafish
