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Related Experiment Video

Updated: Mar 21, 2026

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
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Enhancing Working Memory Training with Transcranial Direct Current Stimulation.

Jacky Au1,2, Benjamin Katz3, Martin Buschkuehl2

  • 1University of California, Irvine.

Journal of Cognitive Neuroscience
|May 12, 2016
PubMed
Summary
This summary is machine-generated.

Transcranial direct current stimulation (tDCS) enhanced working memory (WM) training performance. Effects persisted long-term, with spaced tDCS showing stronger results and right prefrontal stimulation leading to skill transfer to new tasks.

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Area of Science:

  • Cognitive Neuroscience
  • Neuroscience
  • Psychology

Background:

  • Working memory (WM) is crucial for complex cognition but has limited capacity.
  • WM training interventions aim to improve WM-related skills.
  • Transcranial direct current stimulation (tDCS) modulates brain activity and plasticity, offering potential cognitive enhancement.

Purpose of the Study:

  • To evaluate the efficacy of tDCS as a supplement to WM training.
  • To investigate the impact of tDCS on training performance and long-term retention.
  • To explore the effects of stimulation timing and location on WM enhancement.

Main Methods:

  • Sixty-two participants were randomized into three groups: right prefrontal tDCS, left prefrontal tDCS, or sham stimulation.
  • Participants underwent seven sessions of visuospatial WM training concurrently with tDCS.
  • Training performance, retention, and transfer to untrained tasks were assessed.

Main Results:

  • tDCS significantly enhanced WM training performance.
  • Performance gains were notably preserved several months post-training.
  • Spaced tDCS application (over a weekend) yielded stronger effects than daily stimulation.
  • Right prefrontal tDCS demonstrated selective transfer to untrained visual and spatial WM tasks.

Conclusions:

  • tDCS can effectively supplement WM training, leading to durable improvements.
  • Optimizing tDCS application timing and location can maximize cognitive benefits.
  • tDCS holds promise for enhancing performance in WM-intensive learning contexts.